| # | Name | Origin | Meaning | Gender | |
|---|---|---|---|---|---|
| 441 | Elvira | Spanish | Truth. White or beautiful. Famous bearers: the heroine of Noel Coward's play 'Blithe Spirit'; A character in the legend of Don Juan. | F | |
| 442 | Elvita | Spanish | Truth. | F | |
| 443 | Ema | Spanish | Grandmother. | F | |
| 444 | Emanuel | Spanish | With us is God. Variant of Hebrew name Immanuel. A biblical name-title applied to the Messiah. | M | |
| 445 | Emerald | Spanish | The prized green emerald gemstone. | F | |
| 446 | Emesta | Spanish | Serious. | F | |
| 447 | Emesto | Spanish | Serious. | M | |
| 448 | Emilia | Spanish | Flattering. | F | |
| 449 | Emilie | Spanish | Flattering. | F | |
| 450 | Emilio | Spanish | Flattering. | M | |
| 451 | Encarnacion | Spanish | Reference to the Incarnation. | F | |
| 452 | Eneas | Spanish | Praised. | M | |
| 453 | Engracia | Spanish | Graceful. | F | |
| 454 | Enrica | Spanish | Rules her household. Feminine of Henry. | F | |
| 455 | Enriqua | Spanish | Ruler. | F | |
| 456 | Enrique | Spanish | Rules his household. Variant of Henry. | M | |
| 457 | Enriqueta | Spanish | Ruler. | F | |
| 458 | Enzo | Spanish | Rules his household. Variant of Henry. | M | |
| 459 | Erasmo | Spanish | Friendly. | M | |
| 460 | Erendira | Spanish | Name of a princess. | F | |