| # | Name | Origin | Meaning | Gender | |
|---|---|---|---|---|---|
| 421 | Rodrigo | Spanish | Famous ruler. | M | |
| 422 | Rogelio | Spanish | Famous soldier. Renouned spearman. | M | |
| 423 | Roldan | Spanish | Famous. | M | |
| 424 | Roman | Spanish | From Rome. | M | |
| 425 | Romano | Spanish | From Rome. | M | |
| 426 | Romeo | Spanish | From Rome. | M | |
| 427 | Ronaldo | Spanish | Rules with counsel. Form of Ronald. | M | |
| 428 | Roque | Spanish | Rock. | M | |
| 429 | Rosario | Spanish | Rosary. Refers to devotional prayers honoring Mary. | M | |
| 430 | Ruben | Spanish | See, a son!. | M | |
| 431 | Rufio | Spanish | Red haired. | M | |
| 432 | Rufo | Spanish | Red haired. | M | |
| 433 | Sabino | Spanish | A Sabine. | M | |
| 434 | Sal | Spanish | Savior. Diminutive of Salvador. | M | |
| 435 | Salbatore | Spanish | Savior. | M | |
| 436 | Salomon | Spanish | Peace. Variant of Shalom. | M | |
| 437 | Salvador | Spanish | Savior. | M | |
| 438 | Salvadore | Spanish | Savior. | M | |
| 439 | Salvatore | Spanish | Savior. | M | |
| 440 | Salvino | Spanish | Savior. Diminutive of Salvador. | M | |